When to stop metformin/prometrium?

blaine06 · 02-12-2011, 03:04 PM

if you were on metformin or prometrium while pregnant, i'm curious when your doctor took you off of them. my RE told me i could stop metformin at any time and prometrium at 10 weeks. With my h/o miscarriage, i'm very nervous about stopping them, especially the prometrium. at what point in your pregnancy did you ladies stop them?

maelan · 02-12-2011, 03:39 PM

I stopped the met around 12-13 wks. The prometrium ( I was on prog in oil injections before that) at around 11-12 wks.

In hindsight I wish that I would have stayed on the prog longer because I started to bleed from a subchorionic bleed and my OB thinks that stopping the prog didn't help the situation. So I was put on p17 shots. But this is not the norm.

Most dr have you cont on met and prog thru the 1st tri.

blondie · 02-12-2011, 05:01 PM

I stopped Prometrium after the 11wk appt with RE.
I did not stop Metformin--at 11wk appt with RE-he had me reduce to 1000mg/day (from 2000/day). OB also wanted me to stay on it to reduce risk of GD. I had no problems passing GTT test. I also hoped staying on it would help BF too-but, no such luck (too many other factors caused problems with that). Still on only 1000/day per RE. Will up it again to 2000/day month before TTC again.
Good luck!

Jen0653 · 02-12-2011, 05:10 PM

I can only comment about the Met, but both my RE and OB said to stay on it through the first trimester. I ended up taking 500 mg during my 13th week (down from 1000 mg) and then completely stopped in my 14th week. I didn't start gaining weight until I stopped taking it either.

esarah · 02-12-2011, 05:16 PM

I stopped prometrium at 12 weeks and I stayed on metformin the entire time with all of my pregnancies. I stopped long enough to do the GD test and then got back on. I also had P-17 shots with my last two but mine was because of a history of preterm birth. I have had three premature infants.

flutter · 02-12-2011, 11:03 PM

I stopped progesterone suppositories at 12 weeks and took 1000 mg of met per day until 24 weeks then I stopped it for 4 weeks to take my GTT test at 28 weeks and then started it back up when I failed the 1 hour. I didn't take the 3 hour, but decided to monitor my levels and change my diet, I ended up with GD and had to switch from Met to Glyburide after 30 weeks because the met wasn't controlling my sugar as well as I wanted. My OB was fine with me stopping the met at 16 weeks, but I felt like I needed it and think it helped keep my weight gain under control as well as my blood sugar.

jessicaileen · 02-13-2011, 08:23 AM

I stopped Met the day I had my first u/s which was 6.5 weeks - my RE doesn't believe Met helps in any way. I had no problems with my GTT one hour test, passed with flying colors. I stopped PIO injections the day I started into my 12th week.

02-12-2011, 03:04 PM	#1
blaine06 Member Join Date: May 2010 Posts: 55	When to stop metformin/prometrium? if you were on metformin or prometrium while pregnant, i'm curious when your doctor took you off of them. my RE told me i could stop metformin at any time and prometrium at 10 weeks. With my h/o miscarriage, i'm very nervous about stopping them, especially the prometrium. at what point in your pregnancy did you ladies stop them? __________________ 01/18/2011:BFP! It's A BOY! PAUL TURNER REICHART DUE 09/25/2011 Beautiful Baby Boy Born 09/17/2011 at 10:18 am! What a wonderful blessing!

02-12-2011, 03:39 PM	#2
maelan Senior Member PCOSuperStar! Join Date: Feb 2006 Location: Texas Posts: 4,040	I stopped the met around 12-13 wks. The prometrium ( I was on prog in oil injections before that) at around 11-12 wks. In hindsight I wish that I would have stayed on the prog longer because I started to bleed from a subchorionic bleed and my OB thinks that stopping the prog didn't help the situation. So I was put on p17 shots. But this is not the norm. Most dr have you cont on met and prog thru the 1st tri. __________________ Reneé TTC #1 since 10/2003 8 clomid cyles, 6 Follistim cycles and 5 IUI all bfn IVF#1 (7/10): BFP 8/6/10 m/c @ 7.5 weeks IVF#2 (10/10): BFP 11/11/10 Evan Joseph and Nicholas James born 3/16/11 @ 22w1d A moment in our arms, Forever in hearts FET #1 (9/2011): Cancelled due to decreasing e2 levels, thin lining and fluid in uterus...O'd naturally FET#2 (10/2011): BFP 11/8/11 decreasing beta m/c @ 5w IVF #3: 1/12 BFN FET #3: 4/12 BFN FET #4: 9/12 BFP Baby Boy due 5/19/13

02-12-2011, 05:01 PM	#3
blondie Senior Member Join Date: Nov 2008 Location: TX Posts: 662	I stopped Prometrium after the 11wk appt with RE. I did not stop Metformin--at 11wk appt with RE-he had me reduce to 1000mg/day (from 2000/day). OB also wanted me to stay on it to reduce risk of GD. I had no problems passing GTT test. I also hoped staying on it would help BF too-but, no such luck (too many other factors caused problems with that). Still on only 1000/day per RE. Will up it again to 2000/day month before TTC again. Good luck! __________________ Me 38 DH 42 Dx PCOS 3/07 6/07-Clomid res. 7/07-1/08-IUI x5=BFN IVF#1 7/08 OHSS FET#1 9/08 no ET IVF#2 11/08 3 d3=BFN IVF#3 1/09 4 d2=BFN IVF#4 4/09 11 blasts frozen FET #2 6/09 3 blasts=BFN FET #3 10/09 3 blasts=BFN IVF #5 2/10 2d5=BFP! It's a GIRL! cerclage@14wks IC, PROM@32wks, born@33wks (18days in NICU) TTC#2 FET 2/12-BFP! It's a boy cerclage @13wks, bed rest for 10.5 wks!

02-12-2011, 05:10 PM	#4
Jen0653 Senior Member Join Date: May 2009 Location: Michigan Posts: 580	I can only comment about the Met, but both my RE and OB said to stay on it through the first trimester. I ended up taking 500 mg during my 13th week (down from 1000 mg) and then completely stopped in my 14th week. I didn't start gaining weight until I stopped taking it either. __________________ Me 30/ DH 31---> Married 10+ Years 52 pounds lost!!! Several Clomid and Femara Cycles - No Response Several Cycles with Injectables - One No Response, One Overstimmed and O'd twice, but all BFN Resting for a cycle . . . Surprise! BFP on 11/11

02-12-2011, 05:16 PM	#5
esarah Senior Member PCOSuperStar Platinum! Join Date: Jan 2005 Location: UT Posts: 6,508	I stopped prometrium at 12 weeks and I stayed on metformin the entire time with all of my pregnancies. I stopped long enough to do the GD test and then got back on. I also had P-17 shots with my last two but mine was because of a history of preterm birth. I have had three premature infants. __________________ ~Sarah (32) DH (34) Four Children here on Earth Leata 6 Taylor 4 Mark 2 Luke 1 16 Angel Babies

02-12-2011, 11:03 PM	#6
flutter Senior Member PCOStar! Join Date: May 2009 Location: kentucky Posts: 1,360	I stopped progesterone suppositories at 12 weeks and took 1000 mg of met per day until 24 weeks then I stopped it for 4 weeks to take my GTT test at 28 weeks and then started it back up when I failed the 1 hour. I didn't take the 3 hour, but decided to monitor my levels and change my diet, I ended up with GD and had to switch from Met to Glyburide after 30 weeks because the met wasn't controlling my sugar as well as I wanted. My OB was fine with me stopping the met at 16 weeks, but I felt like I needed it and think it helped keep my weight gain under control as well as my blood sugar. __________________ Me 31, DH 33 5/09-8/09 Clomid Resistant 1/10 Gonal F No response 2/10 Gonal F + Menopur BFP 3/06/10! Beta #1 69 #2 only 89 #3 172 3/25/10 Saw HB! Baby girl arrived 11/08/2010! Lost nearly 70 lbs. TTC #2 6/12 Femara 2.5 mg BFN 7/12 Femara 5 mg BFP! 7/29/12 Beta #1 51 It's a BOY! Born 4/4/13

02-13-2011, 08:23 AM	#7
jessicaileen Senior Member PCOSuperStar! Join Date: May 2008 Location: Pittsburgh, Pennsylvania Posts: 3,426	I stopped Met the day I had my first u/s which was 6.5 weeks - my RE doesn't believe Met helps in any way. I had no problems with my GTT one hour test, passed with flying colors. I stopped PIO injections the day I started into my 12th week. __________________ JESSICA 30, DH 31 Married 11/4/2006 *Mommy to two beautiful IVF babies* Oct '09 - FET 10/27/09 = BFP! - Camden Charles born 7/7/10 October 2011 - FET 10/19/11 = BFP! - Austin Jules born 7/1/12

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